Investigation of metabolomic biomarkers for childhood executive function and the role of genetic and dietary factors: The GUSTO cohort
This study suggests that genetically-determined metabolism and, in particular, leucine may be responsible for effects on child cognitive regulation skills, thus dietary interventions may be less efficacious for cognitive development than suggested by previous studies.
Facemask shortage and the novel coronavirus disease (COVID-19) outbreak: Reflections on public health measures.
Without effective public communication, a universal facemask wearing policy could result in societal panic and subsequently, increase the nationwide and worldwide demand for facemasks. These increased demands could cause a facemask shortage for healthcare workers and reduce the effectiveness of outbreak control in the affected regions. (EClinicalMedicine. 2020)
A population-based phenome-wide association study of cardiac and aortic structure and function.
Our study illustrates how population-based cardiac and aortic imaging phenotypes can be used to better define cardiovascular disease risks as well as heart–brain health interactions, highlighting new opportunities for studying disease mechanisms and developing image-based biomarkers. (Nature Medicine. 2020)
The association of air pollution with body mass index: evidence from Hong Kong's "Children of 1997" birth cohort.
Sex-specific associations of air pollutants with adiposity should give impetus to the investigation of their physiological effects, possibly operating as endocrine disruptors. (International Journal of Obesity. 2019)
DNA methylation in blood as a mediator of the association of mid-childhood body mass index with cardio-metabolic risk score in early adolescence.
Our high-dimensional mediation analysis shows a complex role of DNA methylation in the association between body-mass index and cardiometabolic risk. (Epigenetics. 2018)